What does Nobivac Pi protect against?
For active immunisation of dogs from the age of 8 weeks onwards to reduce clinical signs of canine para influenza infection and to reduce viral shedding.
What is the onset of immunity for Nobivac Pi?
Onset of immunity: 4 weeks after vaccination. See the section below on Pi intervals.
What is the duration of immunity for Nobivac Pi?
Duration of immunity: has not been demonstrated, but an anamnestic response is produced in dogs given a revaccination one year after basic vaccination.
Can Nobivac Pi be used in pregnancy?
Nobivac Pi has been shown to be safe for use in pregnant bitches that have been vaccinated before pregnancy with the Pi vaccine of the Nobivac series.
We do not hold specific data regarding use during lactation and therefore cannot recommend this use during this period.
What are the storage requirements for Nobivac Pi?
Nobivac Pi requires storage in a refrigerator between 2oC and 8oC. Do not freeze. Protect from light. Care should be taken to avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use.
Are there any breed specific contraindications for Nobivac Pi?
There are no breed specific contraindications for Nobivac Pi.
Can Nobivac Pi be mixed with other Nobivac vaccines?
Safety and efficacy data (viral excretion) are available which demonstrate that this vaccine can be mixed and administered with the inactivated vaccines of the Nobivac series against canine leptospirosis caused by all or some of the following serovars: L. interrogans serogroup Canicola serovar Canicola, L. interrogans serogroup Icterohaemorrhagiae serovar Copenhageni, L. interrogans serogroup Australis serovar Bratislava, and L. kirschneri serogroup Grippotyphosa serovar Bananal/Liangguang.
The product information of the relevant Nobivac vaccines should be consulted before administration of the mixed product. When mixed with Nobivac leptospirosis vaccines at annual revaccination, it has been established that there is no interference with the anamnestic response induced by the injectable canine parainfluenza virus component.
After administration with one of the leptospirosis vaccines, a mild and transient increase in body temperature (≤ 1°C) may occur for a few days after vaccination, with some pups showing less activity and/or a reduced appetite. A small transient swelling (≤ 4 cm), which can occasionally be firm and painful on palpation, may be observed at the site of injection. Any such swelling will either have disappeared or be clearly diminished by 14 days post-vaccination.
After mixed administration of an overdose of Nobivac Pi and an overdose of the leptospirosis vaccines of the Nobivac series, transient local reactions such as diffuse to firm swellings from 1 to 5 cm in diameter may be observed, usually these will persist no longer than 5 weeks, however some may take a little longer to completely disappear.
Safety and efficacy data are available which demonstrate that this vaccine can be mixed and administered with the inactivated vaccine of the Nobivac series against rabies or the inactivated vaccine against rabies and leptospirosis, where applicable. After administration with the rabies containing vaccines transient local reactions such as diffuse to firm swellings from 1 to 4 cm in diameter may be observed for up to 3 weeks after vaccination. The swellings may be painful for up to 3 days post dosing.
When Nobivac Pi is used with any of the other Nobivac vaccines referred to above, the minimum vaccination age for each vaccine must be taken into account such that at the time of vaccination, the dogs are at or older than the oldest minimum vaccination age for the individual vaccines.
No information is available on the compatibility of this vaccine when used with any other veterinary medicinal product except the products mentioned above. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Note that we do not recommend physical mixing of Nobivac Pi with both Nobivac leptospirosis and rabies vaccines in the same syringe- this 3 vaccine combination would constitute an off-label use for which there is not adequate data.
Note also that the use of Nobivac Lepto2 with or without Nobivac canine freeze-dried vaccines is on-label with respect to concurrent vaccination with Nobivac Rabies (i.e. at a separate injection site). In respect of Nobivac L4 and Rabies vaccination, concurrent use or mixing of these two products remains off-label use at the current time
What is the interval for Nobivac Pi for primary course?
• Before the age of 12 weeks:
Two vaccinations, each with a single dose: the first vaccination from the age of 8 weeks onwards and the second vaccination 2 - 4 weeks later.
• From the age of 12 weeks onwards:
Single vaccination, with one dose per animal.
What is the revaccination protocol for Nobivac Pi?
Every year with a single dose.
Further information is available from the SPC, Datasheet or package leaflet.
Not answered your question?
Nobivac® Pi contains live attenuated canine parainfluenza virus (strain Cornell). POM-V.
Nobivac® Lepto 2 contains inactivated Leptospira interrogans serogroup canicola (strain Ca-12-000) and icterohaemorrhagiae (strain 820K). POM-V.
Nobvac® L4 contains inactivated Leptospira strains: L. interrogans serogroup Canicola serovar Portland-vere (strain Ca-12-000), L. interrogans serogroup Icterohaemorrhagiae serovar Copenhageni (strain Ic-02-001), L. interrogans serogroup Australis serovar Bratislava (strain As-05-073) and L. kirschneri serogroup Grippotyphosa serovar Dadas (strain Gr-01-005). POM-V.
Nobivac® Rabies contains inactivated Rabies virus (strain Pasteur). POM-V.
MSD Animal Health UK Limited. Registered office Walton Manor, Walton, Milton Keynes MK7 7AJ, UK. Registered in England & Wales no. 946942.
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