Bovilis® INtranasal RSP™ Live Questions and Answers
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What does Bovilis INtranasal RSP Live provide protection against?
For active immunisation of calves from the age of 1 week old onwards to reduce clinical signs of respiratory disease and viral shedding from infection with Bovine Respiratory Syncytial Virus and Parainfluenza Virus 3.
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What is the onset of immunity for Bovilis INtranasal RSP Live?
The onset of immunity for Bovine Respiratory Syncytial Virus is 5 days and Parainfluenza Virus 3 is 1 week.
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What is the duration of immunity for Bovilis INtranasal RSP Live?
The duration of immunity is 12 weeks.
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What is the protocol for use for Bovilis INtranasal RSP Live?
Nasal use. Vaccinate calves of 1 week of age onwards.
Reconstitute lyophilisate with solvent as described below. Ensure that the lyophilisate is completely reconstituted before use. The reconstituted vaccine is an off-pink or pink coloured suspension.
Administer a single dose of 2 ml reconstituted vaccine per animal, 1 ml in each nostril.
Instructions for reconstitution:
For proper reconstitution of the lyophilisate, transfer the solvent to the vial with the lyophilisate (2 ml for the 1 dose, 10 ml for the 5 dose and 20 ml for the 10 dose; also see the table below) using a needle and syringe. The vacuum in the vaccine vial will allow quick emptying of the syringe. Then resuspend by shaking.
The vaccine suspension can be drawn up in a syringe with a clean tip. The vaccine in the syringe is now ready for administration, directly from the tip of the syringe. A spraying device is not required.
When vaccinating animals, it is recommended to change syringes or tips of a multi-dose syringe between animals to avoid transmission of pathogens.
Doses per vial
Solvent volume required
Dose volume
1
2ml
2ml
5
10ml
2ml
10
20ml
2ml
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What are the storage requirements for Bovilis INtranasal RSP Live?
Lyophilisate: Store in a refrigerator (2°C – 8°C). Do not freeze. Protect from light.
Solvent: Store below 25°C if stored independently from the lyophilisate. Do not freeze.
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What is the shelf life of Bovilis INtranasal RSP Live once reconstituted?
The shelf life of Bovilis INtranasal RSP Live is 6 hours once reconstituted.
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What is the withdrawal period following Bovilis INtranasal RSP Live?
The withdrawal period following Bovilis INtranasal RSP Live is zero days.
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Can Bovilis INtranasal RSP Live be used in pregnancy or lactation?
Bovilis INtranasal RSP Live is not licensed for use during pregnancy or lactation.
Further information is available from the SPC, Datasheet or package leaflet.
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Bovilis® INtranasal RSP™ Live, Nasal Spray, Lyophilisate and Solvent for Suspension for Cattle, contains live Bovine Respiratory Syncytial virus (BRSV) and live Bovine Parainfluenza virus (PI3) vaccine antigens, POM-V
MSD Animal Health UK Limited. Registered office Walton Manor, Walton, Milton Keynes MK7 7AJ, UK. Registered in England & Wales no. 946942.
Advice should be sought from the medicine prescriber.
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