Bovilis^® BVD Questions and Answers

For active immunisation of cows and heifers from eight months of age onwards to protect the foetus against transplacental infection with bovine viral diarrhoea virus.

Safety and efficacy data are available which demonstrate that for the intramuscular revaccination – in cattle from 15 months of age onwards (i.e. those that have previously had separate primary courses of Bovilis IBR Marker Live and Bovilis BVD) - this vaccine can be mixed and administered with Bovilis BVD. The product literature of Bovilis BVD should be consulted before administration of the mixed products. The adverse effects observed after administration of one dose or an overdose of the mixed vaccines are not different from those described for the vaccines administered separately.

As per the datasheet for Bovilis Leptavoid-H, it states “Safety and efficacy data are available which demonstrate that this vaccine can be administered to animals of 8 months of age or older on the same day, with Bovilis BVD vaccine. The two vaccines should be administered at separate sites. For the concurrent use of Bovilis Leptavoid-H and Bovilis BVD vaccines in naïve animals, the primary vaccination course must be completed at least 4 weeks before the expected gestation, in order that foetal protection can be established. No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product except the product mentioned above. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.”

Foetal protection can be expected if the primary immunisation has been finalised 4 weeks before start of the gestation.

Animals which are vaccinated later than 4 weeks before gestation or during the early gestation will not be protected against foetal infection.

Bovilis BVD is licensed to be given in pregnancy.

Bovilis BVD requires storage in a refrigerator between 2 °C and 8 °C. Do not freeze.

Intramuscular injection. 2 ml per animal.

Herd vaccination

Basic immunisation: Two vaccinations with an interval of 4 weeks. For use in cattle from eight months of age, all animals should be vaccinated.

Revaccination: One vaccination 6 months after basic vaccination with next re-vaccinations at an interval no greater than 12 months.

Individual vaccination

Basic immunisation: Two vaccinations with an interval of 4 weeks. The second vaccination should be given not later than 4 weeks before the start of the gestation. 

Revaccination: One vaccination 4 weeks before start of the next gestation.

All cattle can be vaccinated with Bovilis BVD from an age of eight months onwards.

Shelf life after first opening the immediate packaging: 10 hours.

Shelf life after mixing with Bovilis IBR Marker Live: 3 hours (at room temperature).

The withdrawal period is zero days.