Heptavac® P Plus
The economic impact of losses due to pasteurellosis and clostridial diseases can be devastating. Lamb deaths are only part of the loss. Even surviving lambs are liable to suffer long term losses in condition and weight. While they may look perfectly well, unseen damage to the lungs is common after pneumonia strikes and only becomes apparent when reduced performance leads to later or fewer finished lambs1.
Heptavac P Plus is used for the active immunisation of sheep as an aid in the control of clostridial diseases and pasteurellosis in sheep. Heptavac P Plus contains antigens from six clostridial species and antigens from the most important serotypes of Mannheimia haemolytica and Pasteurella trehalosi.
Presentation
Opaque suspension for injection.
Active ingredients
Each ml of vaccine contains:
Active substances:
Clostridium perfringens beta toxoid ≥ 10 IU*
Clostridium perfringens epsilon toxoid ≥ 5 IU*
Clostridium septicum toxoid ≥ 2.5 IU*
Clostridium tetani toxoid ≥ 2.5 IU*
Clostridium novyi toxoid ≥ 3.5 IU*
Inactivated Clostridium chauvoei ≥ 0.5 guinea pig PD90#
Inactivated Mannheimia haemolytica A1, A2, A6, A7, A9 5x108 cells per strain
Inactivated Pasteurella trehalosi T3, T4, T10, T15 5x108 cells per strain
* International Units of antitoxin, conform Ph.Eur.
# Protective Dose 90%, conform Ph.Eur.
Target species
Sheep.
Indications for use
For the active immunisation of sheep as an aid in the control of lamb dysentery, pulpy kidney, struck, tetanus, braxy, blackleg, black disease, clostridial metritis caused by Clostridium perfringens types B, C and D, Cl. septicum, Cl. novyi, Cl. chauvoei and Cl. tetani. The vaccine may be used as an aid in the control of pneumonic pasteurellosis in sheep of all ages from a minimum age of 3 weeks and in the control of systemic pasteurellosis in weaned fattening and breeding sheep.
The vaccine may be used in pregnant ewes as an aid in the control of lamb dysentery, pulpy kidney, tetanus and pasteurellosis in their lambs provided that the lambs receive sufficient immune colostrum during the first 1-2 days of life.
It is essential to give replacement ewes (and rams) two 2 ml doses, 4 to 6 weeks apart when they join the flock. An annual booster dose is also required 4-6 weeks pre lambing to maintain the ewe’s immunity and to provide high levels of antibodies that can be passed on to her lambs via the colostrum.
Withdrawal periods
Sheep - meat 0 days
Packaging
Low density polyethylene bottle of 50, 100, 250 or 500 ml with rubber closure and aluminium cap.
Legal category
POM-VPS
Further information is available from the SPC, datasheet or package leaflet.
Advice should be sought from the medicine prescriber.
Prescription decisions are for the person issuing the prescription alone.
Use Medicines Responsibly.
Product images are representations of packaging and may not accurately reflect the current packaging available in the GB marketplace.
Date of preparation: September 2025
References
1. Lima et al. (2020). Sustainable lamb production: Evaluation of factors affecting lamb growth using hierarchical, cross classified and multiple memberships models Preventative Veterinary Medicine; 174 (2020) 104822