Bravoxin® 10 Questions and Answers
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What does Bravoxin 10 provide protection against?
For the active immunisation of sheep and cattle against disease associated with infections caused by Clostridium perfringens type A, C. perfringens type B, C. perfringens type C, C. perfringens type D, Clostridium chauvoei, Clostridium novyi type B, Clostridium septicum, Clostridium sordellii and Clostridium haemolyticum and against tetanus caused by Clostridium tetani.
For the passive immunisation of lambs and calves against infections caused by the above mentioned clostridial species (except C. haemolyticum in sheep).
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What is the onset of immunity for Bravoxin 10?
The onset of immunity is two weeks after the primary vaccination course.
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What is the duration of active immunity for Bravoxin 10?
An anamnestic humoral immune response (immunological memory) to all components was demonstrated 12 months following the primary course of vaccination.
As demonstrated by serology/persistent antibody titre only:
Sheep:
12 months against C. perfringens types A, B, C and D; C. novyi type B; C. sordellii and C. tetani.
< 6 months against C. septicum; C. haemolyticum and C. chauvoei.Cattle:
12 months against C. tetani and C. perfringens type D.
< 12 months against C. perfringens types A, B and C.
< 6 months against C. novyi type B; C. septicum; C. sordellii; C. haemolyticum and C. chauvoei. -
What is the duration of passive immunity for Bravoxin 10?
Duration of passive immunity
As demonstrated by serology/persistent antibody titre only is:For lambs:
At least 2 weeks for C. septicum and C. chauvoei.
At least 8 weeks for C. perfringens type B and C. perfringens type C, and at least 12 weeks for C. perfringens type A; C. perfringens type D; C. novyi type B; C. tetani and C. sordellii.
No passive immunity was observed for C. haemolyticum.For calves:
At least 2 weeks for C. sordellii and C. haemolyticum.
At least 8 weeks for C. septicum and C. chauvoei and at least 12 weeks for C. perfringens type A; C. perfringens type B; C. perfringens type C; C. perfringens type D; C. novyi type B and C. tetani. -
What is the withdrawal period following the use of Bravoxin 10?
The withdrawal period following the use of Bravoxin 10 is zero days.
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What is the percentage for reactions after the use of Bravoxin 10?
75 - 100% of animals vaccinated with Bravoxin 10 may experience reactions to vaccination (mainly temporary swelling at injection site).
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Can the second vaccination of the Bravoxin 10 primary course act as the pre-lambing booster?
To provide passive protection of the offspring, via the colostrum, a single booster dose should be administered between 8 and 2 weeks before parturition, if animals have received a full primary vaccination course before pregnancy.
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What are the storage requirements for Bravoxin 10?
Store and transport refrigerated (2 °C - 8 °C). Do not freeze and protect from light.
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What is the shelf life of Bravoxin 10 once broached?
The shelf life of Bravoxin 10 once broached is 8 hours.
Further information is available from the SPC, Datasheet or package leaflet.
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Bravoxin® 10 contains Clostridia vaccine antigens. POM-VPS
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