Nobivac® Lepto 2 Questions and Answers
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What does Nobivac Lepto 2 protect against?
For active immunisation of dogs to reduce infection with Leptospira interrogans serogroup Canicola and Leptospira interrogans serogroup Icterohaemorrhagiae.
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What is the interval for Nobivac Lepto 2 primary course?
All dogs not previously vaccinated should be vaccinated twice 2 - 4 weeks apart.
Puppies should be at least 6 weeks of age before they receive the first vaccination.
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What is the duration of immunity for Nobivac Lepto 2?
A single annual booster dose is recommended.
The duration of immunity induced by the vaccine was established as at least one year.
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Can Nobivac Lepto 2 be used during pregnancy?
The vaccine has been shown to be safe for use in pregnant bitches which have previously been vaccinated with Nobivac Lepto 2.
We do not hold specific data regarding use during lactation and therefore cannot recommend this use during this period.
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Can Nobivac Lepto 2 be given with other Nobivac vaccinations?
Safety and/or efficacy data are available which demonstrate that this vaccine can be mixed with live vaccines from the Nobivac range containing Canine distemper virus (strain Onderstepoort), Canine adenovirus type 2 (strain Manhattan LPV3), Canine parvovirus (strain 154) and/or Canine parainfluenza virus (strain Cornell).
Safety and/or efficacy data are available which demonstrate that this vaccine can be administered the same day but not mixed with the inactivated rabies (strain Pasteur RIV) vaccine from the Nobivac range.
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Are there any breed specific contraindications for Nobivac Lepto 2?
There are no breed specific contraindications for Nobivac Lepto 2.
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What are the storage requirements for Nobivac Lepto 2?
Nobivac Lepto 2 requires storage in a refrigerator between 2oC and 8oC. Do not freeze. Protect from light.
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Does Nobivac Lepto 2 contain Thiomersal?
Thiomersal is a mercury-containing preservative which is sometimes used in the manufacture of vaccines. None of the small animal freeze-dried vaccines contain mercury. However, some vaccine products available as multi-dose vials in some parts of the world contain trace quantities of mercury as thiomersal or other similar compounds can be vital in ensuring that potentially dangerous bacterial and fungal pathogens do not readily contaminate such vials once broached.
Thiomersal is found in Nobivac Rabies, Nobivac Lepto2 and Nobivac L4. This preservative has not been associated causally with adverse events since its inclusion in human vaccinations in the 1930’s and the amount included in veterinary vaccines is kept to a minimum, in order to ensure bacterial and fungal growth does not occur.
There are no specific safety concerns in relation to the trace amounts of mercury that may be present in veterinary vaccines nor indeed in those that have been used for humans. In contrast, where they are used, they give considerable safety benefits in the day to day use of such products.
Further information is available from the SPC, Datasheet or package leaflet.
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Nobivac® Lepto 2 contains inactivated Leptospira interrogans serogroup canicola (strain Ca-12-000) and icterohaemorrhagiae (strain 820K). POM-V.
MSD Animal Health UK Limited. Registered office Walton Manor, Walton, Milton Keynes MK7 7AJ, UK. Registered in England & Wales no. 946942.
Advice should be sought from the medicine prescriber.
Use medicines responsibly.
