Place the pill between the thumb and index finger of one hand. Hold the top of the cat's head and gently but firmly grasp the cheekbones with the thumb and index finger of the other hand just behind the canine teeth.
Gently tilt the head back until the cat's eyes are facing upward. Usually the cat's jaw will drop open on its own. If not, apply a little pressure on the lower jaw with your middle finger. Bring the pill to the cat's mouth.
Keep your middle finger over the small incisor teeth to keep jaw open. Deposit the pill as far back on the tongue as possible. Immediately close the mouth.
Gently stroke the throat or blow in the nostrils to encourage swallowing. Work fast to avoid being bitten.